[Opgelost] Is LSD good for Generalized Anxiety Disorder (GAD)

Absolutely! Based on both clinical research and extensive therapeutic experience, LSD-assisted therapy can be a highly promising approach for Generalized Anxiety Disorder (GAD), particularly in cases like yours where ketamine has provided relief, but you’re looking for something potentially deeper or more durable.

1. Can LSD help with GAD and severe anxiety?

Yes, and the evidence is becoming increasingly strong. A recent Phase 2b clinical trial published in JAMA found that a single guided LSD session (~100 µg) led to:

1. A 65% response rate and 48% remission rate at 12 weeks

2. Large reductions in anxiety symptoms — often within days

3. Sustained benefits lasting weeks to months

4. Deep emotional breakthroughs, not just symptom suppression

What makes LSD especially effective for GAD is that it doesn’t numb the anxiety like traditional medications or even ketamine might. Instead, it helps rewire how the brain relates to uncertainty, fear, and rumination — the core emotional engines behind generalized anxiety.

2. How LSD differs from ketamine

Since you’re already doing IV ketamine every 4–6 weeks, you likely respond well to neuroplastic interventions. LSD builds on this, but in a different way:

Ketamine:

1. Works fast

2. Dampens symptoms

3. Requires frequent maintenance

4. Stabilizes emotional state

LSD:

1. Produces a deep insight-driven journey

2. Targets the root patterns (worry loops, hypervigilance, emotional rigidity)

3. May require just 1–3 sessions

4. Helps restructure your emotional and cognitive frameworks

In short: ketamine soothes; LSD transforms. They’re not in competition — they’re complementary tools when used intentionally.

3. Is your situation a good fit?

From what you’ve shared, the answer is yes — with proper support:

✅ You’re stable and off medications
✅ You’re already benefiting from psychedelic-assisted therapy (ketamine)
✅ Your anxiety seems chronic, not episodic. This fits the profile where LSD shows the strongest results
✅ You’re open to professional guidance

The only caution is that severe anxiety can intensify the psychedelic experience, especially during the peak. That’s why a guided LSD session with proper preparation, a moderate dose, and thorough integration is essential. At Triptherapie, we offer sessions with legal LSD analogs that mimic LSD-25 in effect, in a safe and structured setting.

4. Spacing with ketamine

To maximize the clarity and impact of an LSD session, it’s wise to pause ketamine for at least 2 weeks before and after. This isn’t just about safety, it’s about allowing:

1. Neuroplastic systems to reset (no cross-tolerance)

2. Clean emotional processing from the LSD session

3. A clear integration window without interference

This way, any breakthroughs you have with LSD can consolidate fully, without being overwritten or diluted.

5. Bottom line

LSD-assisted therapy offers a scientifically grounded and deeply experiential approach to working with anxiety and depression. It won’t “cure” you overnight, but it may help shift the very structure of how anxiety lives in your system.

For many clients, one or two sessions produce changes they’ve never achieved through medications or years of talk therapy. And you don’t have to abandon ketamine. Many use it afterward as a stabilizer while the deeper work unfolds.