Histamine and hay fever
For many people, the start of spring also marks the start of hay fever season. Itchy eyes, stuffy noses. Very inconvenient and annoying. There are many remedies on the market to alleviate it. But did you know you need histamine and can reduce its excess naturally?
Histamine is a substance the body can produce itself. It plays a role in stomach acid production, the immune system, and sleep. It also functions as a neurotransmitter and is a signaling substance of the central nervous system. A lot of histamine is found in mast cells, which play a vital role in your immune system. These mast cells are located in tissues that connect to the outside world, such as your skin, lungs, and digestive tract. It only enters the body internally when it passes through the intestinal wall. In addition to mast cells, histamine is also found in your brain.

Complaints
When an allergic reaction occurs, large amounts of histamine are released, increasing local blood flow and increasing the permeability of the blood vessel walls. This allows clotting factors to more easily enter the blood vessel to repair damaged tissues. When an excess of histamine is not tolerated, it's called histamine intolerance. The threshold for an excess varies from person to person. It's not that you're allergic or sensitive, but simply that there's too much of it in your body. Symptoms that can arise include headaches and migraines, but also:
- Heart palpitations
- Nausea, vomiting
- Insomnia
- Intestinal cramps, diarrhea
- Sneezing
- Dizziness
- Itchy skin
- Stuffy nose, runny nose, shortness of breath
- Heat and redness
Causes
Normally, it is broken down by the enzymes MAO, DAO, and NMT. In some people, this process is insufficient. One cause may be that genetic changes cause fewer of these enzymes to be produced. Intestinal problems also affect this. Certain medications (such as dihydralazine, isoniazid, clavulanic acid, promethazine, verapamil, metoclopramide, and ambroxol hydrochloride) or alcohol consumption can also cause reduced DAO enzyme production.
Other DAO blockers include:
- Coffee
- Energy drinks
- Tea (black, green, yerba mate)
Vitamin B6 and vitamin C work closely with the DAO enzyme. When these two vitamins are insufficient, histamine levels will rise. Reduced production causes excess histamine to remain in the blood.
Causes may include:
- Allergies
- Inflammations
- SIBO / unbalanced intestinal flora
- Celiac disease
- Foods
- Long-term use of histamine blockers
- Mastocytosis; this involves the presence of too many mast cells.
People prescribed antihistamines notice a reduction in their current symptoms. However, this can also affect stomach acid production. Heartburn is a consequence of this. In most cases, this is due to a lack of stomach acid rather than an excess. Antacids such as Rennies or similar medications alleviate heartburn, but also hinder proper food digestion. As you can see, everything is interconnected. An antihistamine diet offers a way to reduce symptoms without using medication. A low-histamine diet automatically results in lower histamine levels.
Histamine-rich foods
| Meat | Pork, lamb, game, liver. Dried sausages: ham, salami, cervelat |
| Fish | Mackerel, tuna, cod, herring, sardines, shellfish (including prawn crackers). Canned fish |
| Dairy | Mold cheeses, quark, old cheese, buttermilk, yogurt, sour cream, crème fraîche |
| Vegetables / fruits | Tomatoes, sauerkraut, spinach, beets, soybeans, strawberries, raspberries, kiwi, pineapple, melon, avocado, grapefruit, olives |
| Herbs / spices | Vanilla, cloves, cumin, coriander, chervil, ginger, nutmeg, cinnamon, chili powder, soy |
| Drink | Alcoholic beverages, carbonated drinks |
| Miscellaneous | Chocolate, licorice, menthol. Yeast-rich food |
| Dried fruit | Raisins, plums, dates, figs |
| Fermented foods | Kimchi, sauerkraut, kombucha, pickles |
Histamine releasing foods
| Miscellaneous | Alcohol, sugars |
| Fruits / citrus fruits | Bananas, strawberries, pineapple, grapes, kiwi, mango, papaya, figs, lemon, lime, grapefruit, orange |
| Egg | Egg white |
| Dairy | |
| Nuts and seeds | |
| Meat | Pork |
| Vegetables | Fresh spinach, beetroot, tomato |
| Wheat | |
| Artificial additives | E102. E104, E110, E122 to E124, E128, E154, E155, E180, E249 to E252, Glutamates E621 to E625 |
Low-histamine foods (except those mentioned above)
| Fresh organic grass-fed meat | The above mentioned are excluded |
| Fresh wild-caught fish | |
| Fresh vegetables | Carrots, cauliflower, broccoli, cucumber, sweet potato, pumpkin, parsnip, asparagus, endive, kale, onion, garlic, etc. |
| Fresh fruit | Apples, berries |
| Dairy / substitutes | Young cheese, coconut milk, hemp milk, almond milk, rice milk |
| Siege | Peanut butter, honey, apple syrup |
| Cereals | Gluten free: rice, quinoa, buckwheat, oatmeal |
| Egg | Egg yolk |
| Herbs / spices | Fresh herbs and spices |
| Oil | Olive oil, coconut oil |
*These lists don't include the entire range of foods. But they do provide a broad overview.
Low-histamine diet
If you want to start lowering your histamine levels, it's important to keep your food as fresh as possible. The longer you store something, the higher its histamine content. Raw meat, fish, and poultry carry certain bacteria that ferment the food, with histamine as a byproduct. To combat the natural increase, you can buy fresh food and process it the same day by cooking or freezing it. This plan is meant to raise awareness, not to impose all sorts of restrictions. When you eat a product, enjoy it to the fullest.
This article didn't consider the influence of the products on other bodily processes. It focused solely on the amount of histamine in the product or what stimulates its production. A low-histamine diet can alleviate symptoms in one week. However, it's a short-term solution. Identifying the underlying problem and its cause is crucial for permanently eliminating the intolerance. Rinsing your nose and sinuses is recommended for relieving hay fever symptoms. You can use a Rhinohorn, available at various drugstores or online.
Personal guidance
If you would like more information about the antihistamine diet, low stomach acid, or improving your gut health, please email [email protected]. These components also play a role in preparing for a wonderful psychedelic session. We will always incorporate these into a personalized lifestyle plan that we create for you based on the intake.