What is psilohuasca?
During a psilohuasca ceremony, psilohuasca is served, which causes a psychedelic journey. psilohuasca is a unique combination of psilocybin-containing truffles or mushrooms and the vine used in ayahuasca, the Banisteriopsis Caapi. Psilocybin in itself is a powerful psychedelic substance that can induce altered states of consciousness that can promote healing, growth and transformation. Psilocybin can help you access your subconscious, release emotional blocks, gain insights and connect with your true self. By adding the MAO inhibitor Banisteriopsis Caapi, the effects of psilocybin can be enhanced by prolonging, deepening and clarifying the trip.
Spiritual effects psilohuasca
Those who prefer psilohuasca over the truffle ceremony are more often looking for spiritual and mystical experiences. Firstly, the psilohuasca during the ceremonies often contains higher doses of psychedelic substances than the truffle ceremony. The strengthening effect of the added MAO inhibitor on top of psilocybin also contributes to the depth of the trip. In addition, the Banisteriopsis Caapi has a sacred status in various cultures and the plant is often used in religious and spiritual rituals. Customers often choose the psilohuasca ceremony with the intention of gaining a mystical experience. We then help with the preparation to adapt where a spiritual character is present. A small disadvantage of psilohuasca is the additional physical discomfort.
Free choice psilohuasca, psiloflora or psilocybin
During the truffle ceremonies that we organize, we give everyone the option to choose additions. This way we can turn every truffle ceremony into a psilohuasca ceremony by adding the Banisteriopsis Caapi. Psiloflora is also possible, because then we add the Passiflora Incarnata. For people who prefer no additives or who cannot do so due to medication, we can increase the psilocybin dosage to such an extent that the additives are not even necessary to cause a strong and deep trip. However, when booking a ceremony, it is useful to indicate your preference for a combination so that we can provide the correct dietary advice.
Difference between psiloflora and psilohuasca ceremony
Psilocybin is responsible for the hallucinogenic effects of both psiloflora and psilohuasca. MAOi, or monoamine oxidase inhibitors, are substances that slow down the breakdown of certain neurotransmitters, psychedelics, so that they remain active for longer and therefore have a greater effect. Both psilohuasca and psiloflora are combinations of psilocybin and an MAOi, which are used for spiritual and therapeutic purposes. The combination of psilocybin and MAOi strengthens and prolongs the effect of psilocybin, allowing the user to have deeper and more intense experiences. The rich and intense visual hallucinations are often mentioned as an additional benefit
Psilohuasca is prepared by combining psilocybin-containing mushrooms or truffles with a MAOi-containing plant that is often used with ayahuasca, the Banisteriopsis Caapi. Psiloflora is prepared by combining psilocybin with milder MAOi from the passion flower, Passiflora Incarnata. The advantage over psilohuasca is that psiloflora has less risk of increasing blood pressure, causing interactions with other medications or foods, and causing physical discomfort. Psiloflora also does not require a strict diet before or after ingestion, as psilohuasca does. Psiloflora is therefore gentler on the body and has less chance of complications.
The power of the passion flower
Passionflower has been used for centuries by the indigenous peoples of the Americas as a sedative and sleep inducing agent. Also in Europe, passion flower was introduced as a folkloric medicine for anxiety, nervousness, insomnia and epilepsy.
Passionflower is beneficial to health because it contains various bioactive substances that have a beneficial effect on the nervous system, cardiovascular system, immune system and skin.
The most important MAOi in passiflora incarnata are harman, harmin, harmaline, harmol and harmalol. These substances have a structural similarity to serotonin and can bind to the serotonin and GABA receptors in the brain. This gives them a calming, relaxing and antidepressant effect. These indole alkaloids mainly inhibit the MAO-A subtype, which is involved in the breakdown of serotonin and norepinephrine.
Another MAOI in passiflora incarnata is chrysin, a flavonoid that also has anti-inflammatory and antioxidant effects. Chrysin mainly inhibits the MAO-B subtype, which is mainly involved in the breakdown of dopamine and phenylethylamine. This gives chrysin a stimulating, cognitively improving and neuroprotective effect.
Psiloflora vs. psilocybin
Psilocybin is seen as the psychoactive substance that causes the psychedelic effects. Although psilocybin has a psychoactive effect, it is relatively small compared to psilocin. Psilocin occurs to a lesser extent in mushrooms and truffles, but oxidizes faster than psilocybin. Most effects come from psilocybin, which is converted to psilocin after ingestion. This process occurs when psilocybin is metabolized by the body. This causes a molecule to lose its phosphate group, resulting in the formation of psilocin.
Psilocin has a similar structure to psilocybin and serotonin and can easily cross the blood-brain barrier. This allows it to bind to the serotonin receptors in the brain, leading to its hallucinogenic effects.
After conversion from psilocybin, psilocin is more sensitive to the oxidation processes catalyzed by naturally occurring MAO enzymes. Oxidized psilocybin and psilocin lose their psychoactive effect. An MAO inhibitor such as in passion flower keeps the MAO enzymes occupied, so that psychedelics remain active for longer and relatively less of them are needed. An additional advantage of psiloflora are the aforementioned soothing effects that provide a calm, dreamy trip.
Contraindications psilohuasca
There are more contraindications to the use of psilohuasca than to the use of psilocybin alone. We must investigate in advance whether our participants are suitable. First, the contraindications for psilocybin still apply since psilocybin is part of the mix. In addition, there are restrictions on the use of strong MAO inhibitors.
- Pregnancy
- Kidney diseases
- Diabetes
- Epilepsy
- Neurological disorders
- High bloodpressure
- Heart and vascular disease
- Brain hemorrhages
- Adrenal gland complaints
- Abnormal blood cells
- Schizophrenia
- Psychosis sensitivity
- Borderline
- SSRi: citalopram (Cipramil®) – escitalopram (Lexapro®) – fluoxetine (Prozac®) – fluvoxamine (Fevarin®) – paroxetine (Seroxat®) – sertraline (Zoloft®) etc…
- SNRi: Venlafaxine (Efexor) – Duloxetine (Cymbalta) etc…
- TCA: mitriptyline (Tryptizol®) – clomipramine (Anafranil®) – imipramine – nortriptyline (Nortrilen®) etc….
- Benzodiazepines: oxazepam (Seresta), – diazepam (Valium) – alprazolam (Xanax) etc…
- Anti-asthmatic agents
- Medicines for high blood pressure: (methyldopa, guanethidine, reserpine)
- Buspirone
- Levodopa
- Opoids (in particular dextromethorphan (found in cough syrup, among other things), tramadol!) morphine and codeine
- Remedies for colds, nasal congestion and cough syrups (if available). dextromethorphan or sympathomimetics contain) (Otrivin® and others)
- Sibutramine (remedy for obesity)
- Sympathomimetics. (amphetamines, cocaine, methylphenidate (Ritalin®, Concerta® and Equasym®), dopamine, adrenaline, norepinephrine, isoproterenol)
- Psychedelics such as LSD, MDMA, Ketamine and all other mind altering substances
- Weed or Marijuana
- Amphetamines
- Anesthetics
- Ephedra and other strong weight loss agents
- Iboga/Ibogaine (stop taking it a month in advance)
Psilohuasca/Ayahuasca diet
The MAO inhibitors of ayahuasca and psilohuasca can become a problem in combination with various foods. We recommend following a tyramine-restricted diet. Tyramine can be a problem with strong MAO inhibitors. In the case of psiloflora, adjusting the diet is not necessary, but it is recommended.
Tyramine
Tyramine plays a role in the regulation of blood pressure. Too much tyramine in your blood can cause high blood pressure, resulting in complaints such as headaches. Normally you do not experience this problem, because certain enzymes break down tyramine. These enzymes have the collective name monoamine oxidase, abbreviated MAO. When using a lot or strong MAOi, the tyramine content can increase and endanger health.
Tyramine can be formed under the influence of bacteria. bacteria form it from the amino acid tyrosine, which is a building block of various proteins. In products containing proteins that are stored or ripened, the tyramine content increases due to the breakdown of tyrosine into tyramine. As a result, old cheese contains much more tyramine than young cheese. Other food processing, including fermentation, fermentation and smoking, increases tyramine levels.
Tyramine-restricted diet
Avoid the following foods for the 3 days before the ceremony:
- Vegetable: sauerkraut
- Herbs: licorice, St. John's wort and ginseng.
- Meat: raw, smoked or cheese-prepared meat and fish.
- Sliced meats: sliced and processed meats
- Dairy: cheese, unpasteurized milk
- Seafood: trassie
- Bread: sourdough bread
- Soy products: tempeh, soy sauce, fish sauce, Tamri and Worcestershire sauce
- Drink: herbal tea with St. John's wort and/or licorice.
- Alcoholic beverages. All alcoholic drinks.
- Yeast: No Marmite, Tartex, brewer's yeast, bread drink and maggi.
- Ready-made: Everything that is not fresh.
Registration for psilohuasca ceremony
Truffle ceremony
Psychedelic Loft Schiedam-
4 January 2025
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8 February 2025
We ask every participant of psychedelic ceremonies to complete the intake. We ask for medical information, intentions and the intake includes a neurotransmitter test. We will examine the information entered and, if we discover any contraindications, we will report them. In some cases, with a minor adjustment, it is still possible to participate in the psilohuasca ceremony with or without Banisteriopsis Caapi or passion flower addition.
We draw up a personal preparation and lifestyle plan after a reservation for the ceremony has been made. We also use the data entered during the online intake for this purpose.
