Medicinal drugs?
Colloquially, drugs are often used to refer to addictive street drugs. However, there are many different substances that fall under the heading of drugs. Some fall under substance abuse, addictive substances or medicinal drugs such as marijuana. The way drugs are used is of course the most important. Recently, hallucinogens in particular and psychedelics without hallucinogenic effects have been in the spotlight when it comes to their therapeutic potential. We therefore see psychedelics as a completely different subvariant of the different types of drugs and psychedelics are therefore the least harmful. This concerns the least harmful and most researched; psilocybin from mushrooms and magic truffles. But LSD and MDMA are also receiving increasing attention.
What do the different psychedelics have in common?
1: BDNF
The various psychedelics are almost all known to increase activity on the serotonin receptors. This is usually done because the psychedelics are similar to serotonin and fit into the same receptors. With some drugs such as MDMA, the activity is increased by releasing more of the body's own stores of serotonin. Overall, most of the effects are achieved through the stimulation of the serotonin receptor 5HT2a. The degree of stimulation of the 5HT2a receptor in particular as well as a mix of other receptors causes a change in perception, mood and the production of new connections in the brain. The new connections in the brain are attributed to the extra production of the neurotrophin BDNF. When the body releases more BDNF, it flips the switch on a series of genes that grow brand new brain cells, nerve cells, and connections. Even slightly higher BDNF ensures that you learn faster, remember better, age more slowly and your brain quickly rearranges the connections with the different parts of the brain and body.
BDNF also increases brain plasticity. When brain cells become damaged or encounter a stressful situation, BDNF protects them and helps them come back stronger. The neural pathways become more flexible rather than broken down, which could explain why higher levels of BDNF are associated with warding off depression.
2: DMN activity
The Default Mode Network (DMN) includes brain areas in the cortex that are normally active during rest and is involved in remembering events, social and emotional judgment, and planning for the future. Reducing the activity of the DMN ensures that the sense of time disappears and people live more in the here and now. This means that worries and fears about the future disappear.
Lower activity of the DMN therefore results in a lower stress level and therefore lower cortisol. Low cortisol ensures that the body can use its self-healing ability to fight diseases and inflammation. Thanks to the reduced inflammation levels, more serotonin is released, which in turn releases more BDNF, while also lowering anxiety and depression.
Read more about being in the now
3: Less ego
Psychedelics in higher doses ensure that the sense of self is put on the back burner because a higher degree of connection can be experienced. The ego usually wants to be fed with more and more and often unhealthy things. The ego makes us restless and anxious as self-preservation is the ego's greatest goal. Without an ego we will not survive, but an overactive ego causes separation, loneliness and addictions.
Less ego means more connectedness, less depression, more serotonin, more BDNF, more healthy choices, less stress and less DMN activity.
4: Emotions are allowed
It regularly happens that during a psilocybin session, emotions arise that have been blocked for a long time. It is precisely the release of this “old pain” that releases emotional blockages and sometimes also psychosomatic complaints. It can sometimes feel liberating to feel everything that needs to be felt without inhibition. Because psychedelics can also give a feeling of satisfaction, the “negative” emotions can often be felt more easily and processed into something that someone can be satisfied with.
5: Hallucinations
At normal doses, MDMA causes almost no hallucinations, while other well-known psychedelics do just that. LSD, psilocybin and DMT (ayahuasca) are known to cause hallucinations. The hallucinations in combination with the effects described above can provide new insights that can help, spiritual experiences or a very beautiful experience that cannot be explained in words. We believe it is also an insight into how the subconscious works and one can make healthy choices sooner with the new knowledge. Do you want to learn more about the hallucinations? Then read more via the link:
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With us, the processes start with the intake form. After completing the intake, initial advice will be sent to you by email containing the recommended trip and dosage. The email also contains an explanation of what the approach will be and how an appointment can be made for the psychedelic session.
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